William Wiley
William Wiley may refer to:
- William Wiley (editor), postal worker who was a civil rights advocate, newspaper editor and publisher, and Providence, Rhode Island Urban League co-founder and president
- William Wiley (sailor), 19th American sailor
- William D. Wiley (born 1971), American politician, Virginia Delegate
- William H. Wiley (1842–1945), U.S. Representative from New Jersey
- William T. Wiley (1937–2021), American contemporary artist